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Amyloid-β Antibody Treatment Leads to Rapid Normalization of Plaque-Induced Neuritic Alterations

The accumulation of amyloid-β into insoluble plaques is a characteristic feature of Alzheimer's disease. Neuronal morphology is distorted by plaques: rather than being essentially straight, they are substantially more curved than those in control tissue, their trajectories become altered, and t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lombardo, Julianne A., Stern, Edward A., McLellan, Megan E., Kajdasz, Stephen T., Hickey, Gregory A., Bacskai, Brian J., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740984/
https://ncbi.nlm.nih.gov/pubmed/14645482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-34-10879.2003
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