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Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice
Senile plaques are a major pathological hallmark of Alzheimer’s Disease (AD). Compelling evidence suggests that senile plaques lead to structural alterations of neuronal processes and that local toxicity may be mediated by increased oxidative stress. Anti-oxidant therapy can alleviate the neuronal a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996241/ https://ncbi.nlm.nih.gov/pubmed/19124175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.11.006 |
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