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Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice

Senile plaques are a major pathological hallmark of Alzheimer’s Disease (AD). Compelling evidence suggests that senile plaques lead to structural alterations of neuronal processes and that local toxicity may be mediated by increased oxidative stress. Anti-oxidant therapy can alleviate the neuronal a...

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Detalhes bibliográficos
Main Authors: Garcia-Alloza, Monica, Borrelli, Laura A., Hyman, Bradley T., Bacskai, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996241/
https://ncbi.nlm.nih.gov/pubmed/19124175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.11.006
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