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A limited role for microglia in antibody mediated plaque clearance in APP mice
Amyloid-β (Aβ) accumulation in senile plaques is a hallmark of Alzheimer’s disease (AD). Immunotherapy is a leading approach for amyloid clearance, despite the early termination of the Elan clinical trial with active immunization due to a few cases of meningoencephalitis. The mechanisms of immunothe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193669/ https://ncbi.nlm.nih.gov/pubmed/17822910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.07.019 |
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