Four-dimensional microglia response to anti-Aβ treatment in APP/PS1xCX3CR1/GFP mice

Senile plaques, mainly composed of amyloid-β (Aβ), are a major hallmark of Alzheimer disease (AD), and immunotherapy is a leading therapeutic approach for Aβ clearance. Although the ultimate mechanisms for Aβ clearance are not well known, characteristic microglia clusters are observed in the surroun...

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Detaylı Bibliyografya
Yayımlandı:Intravital
Asıl Yazarlar: Garcia-Alloza, Monica, Borrelli, Laura A., Thyssen, Diana H., Hickman, Suzanne E., El Khoury, Joseph, Bacskai, Brian J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609732/
https://ncbi.nlm.nih.gov/pubmed/28944103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/intv.25693
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