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Four-dimensional microglia response to anti-Aβ treatment in APP/PS1xCX3CR1/GFP mice
Senile plaques, mainly composed of amyloid-β (Aβ), are a major hallmark of Alzheimer disease (AD), and immunotherapy is a leading therapeutic approach for Aβ clearance. Although the ultimate mechanisms for Aβ clearance are not well known, characteristic microglia clusters are observed in the surroun...
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| Publicado en: | Intravital |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5609732/ https://ncbi.nlm.nih.gov/pubmed/28944103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/intv.25693 |
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