Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs.

In alzheimer's disease, amyloid beta (A beta) is deposited in senile plaques and amyloid angiopathy. Longer A beta peptides, which extend to residue 42 (A beta 42), have been suggested to be critical for the seeding of amyloid. Aged dogs develop cerebral vessel amyloid and parenchymal preamyloi...

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Bibliographic Details
Main Authors: Wisniewski, T, Lalowski, M, Bobik, M, Russell, M, Strosznajder, J, Frangione, B
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216946/
https://ncbi.nlm.nih.gov/pubmed/8573095
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