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In Vivo Imaging of Reactive Oxygen Species Specifically Associated with Thioflavine S-Positive Amyloid Plaques by Multiphoton Microscopy

Amyloid-β, the primary constituent of senile plaques in Alzheimer's disease, is hypothesized to cause neuronal damage and cognitive failure, but the mechanisms are unknown. Using multiphoton imaging, we show a direct association between amyloid-β deposits and free radical production in vivo in...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: McLellan, Megan E., Kajdasz, Stephen T., Hyman, Bradley T., Bacskai, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742052/
https://ncbi.nlm.nih.gov/pubmed/12657680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02212.2003
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