LITAF Regulates Cardiac L-type Calcium Channels by Modulating NEDD4-1 Ubiquitin Ligase

BACKGROUND: The turnover of cardiac ion channels underlying action potential duration (APD) is regulated by ubiquitination. Genome-wide association studies (GWAS) of QT interval identified several single-nucleotide polymorphisms located in or near genes involved in protein ubiquitination. A genetic...

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Udgivet i:Circ Genom Precis Med
Main Authors: Moshal, Karni S., Roder, Karim, Kabakov, Anatoli Y., Werdich, Andreas A., Yi-Eng Chiang, David, Turan, Nilüfer N., Xie, An, Kim, Tae Yun, Cooper, Leroy L., Lu, Yichun, Zhong, Mingwang, Li, Weiyan, Terentyev, Dmitry, Choi, Bum-Rak, Karma, Alain, MacRae, Calum A., Koren, Gideon
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750970/
https://ncbi.nlm.nih.gov/pubmed/31462068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.119.002641
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