The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2

The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval upstream of LITAF (lipopolysaccharide-induced tumor necrosis factor-α factor), a protein encoding a regulator of endosomal trafficking. Howe...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Turan, Nilüfer N., Moshal, Karni S., Roder, Karim, Baggett, Brett C., Kabakov, Anatoli Y., Dhakal, Saroj, Teramoto, Ryota, Chiang, David Yi-Eng, Zhong, Mingwang, Xie, An, Lu, Yichun, Dudley, Samuel C., MacRae, Calum A., Karma, Alain, Koren, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939464/
https://ncbi.nlm.nih.gov/pubmed/33093176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015216
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