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Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

The QT interval is an important diagnostic feature on surface electrocardiograms because it reflects the duration of the ventricular action potential. A previous genome-wide association study has reported a significant linkage between a single-nucleotide polymorphism ∼11.7 kb downstream of the gene...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roder, Karim, Kabakov, Anatoli, Moshal, Karni S., Murphy, Kevin R., Xie, An, Dudley, Samuel, Turan, Nilüfer N., Lu, Yichun, MacRae, Calum A., Koren, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322893/
https://ncbi.nlm.nih.gov/pubmed/30401747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003852
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