Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

The QT interval is an important diagnostic feature on surface electrocardiograms because it reflects the duration of the ventricular action potential. A previous genome-wide association study has reported a significant linkage between a single-nucleotide polymorphism ∼11.7 kb downstream of the gene...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Roder, Karim, Kabakov, Anatoli, Moshal, Karni S., Murphy, Kevin R., Xie, An, Dudley, Samuel, Turan, Nilüfer N., Lu, Yichun, MacRae, Calum A., Koren, Gideon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Protein Synthesis and Degradation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322893/
https://ncbi.nlm.nih.gov/pubmed/30401747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003852
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