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Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

The QT interval is an important diagnostic feature on surface electrocardiograms because it reflects the duration of the ventricular action potential. A previous genome-wide association study has reported a significant linkage between a single-nucleotide polymorphism ∼11.7 kb downstream of the gene...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Roder, Karim, Kabakov, Anatoli, Moshal, Karni S., Murphy, Kevin R., Xie, An, Dudley, Samuel, Turan, Nilüfer N., Lu, Yichun, MacRae, Calum A., Koren, Gideon
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322893/
https://ncbi.nlm.nih.gov/pubmed/30401747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003852
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