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Activation of human ether-a-go-go related gene (hERG) potassium channels by small molecules
Human ether-a-go-go related gene (hERG) potassium (K(+)) channels play a critical role in cardiac action potential repolarization. Mutations that reduce hERG conductance or surface expression may cause congenital long QT syndrome (LQTS). However, the channels can be inhibited by structurally diverse...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085723/ https://ncbi.nlm.nih.gov/pubmed/21623390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.70 |
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