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Novel Intramolecular Photoinduced Electron Transfer-Based Probe for the Human Ether-a-go-go-Related Gene (hERG) Potassium Channel

Drug induced long QT syndrome is a high risk event in clinic, which mainly result from their high affinity with Human Ether-a-go-go-Related Gene (hERG) potassium channel. Therefore, evaluation of the drug’s inhibitory activity against hERG potassium channel is a required step in drug discovery and d...

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Detalhes bibliográficos
Publicado no:Analyst
Main Authors: Liu, Zhenzhen, Zhou, Yubin, Du, Lupei, Li, Minyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658274/
https://ncbi.nlm.nih.gov/pubmed/26526230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an01974e
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