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Astemizole-based turn-on fluorescent probes for imaging hERG potassium channel

Based on the scaffold of astemizole, three novel turn-on fluorescent probes (N1–N3) for human ether-a-go-go-related gene (hERG) potassium channel were developed herein. These probes have reasonable fluorescence properties, acceptable cell toxicity, and potent inhibitory activity, all of which contri...

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Dades bibliogràfiques
Publicat a:Medchemcomm
Autors principals: Zhang, Xiaomeng, Liu, Tingting, Wang, Beilei, Gao, Yuqi, Liu, Pan, Li, Minyong, Du, Lupei
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482408/
https://ncbi.nlm.nih.gov/pubmed/31057730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00562a
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