In silico prediction of hERG potassium channel blockage by chemical category approaches

The human ether-a-go-go related gene (hERG) plays an important role in cardiac action potential. It encodes an ion channel protein named Kv11.1, which is related to long QT syndrome and may cause avoidable sudden cardiac death. Therefore, it is important to assess the hERG channel blockage of lead c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol Res (Camb)
Egile Nagusiak: Zhang, Chen, Zhou, Yuan, Gu, Shikai, Wu, Zengrui, Wu, Wenjie, Liu, Changming, Wang, Kaidong, Liu, Guixia, Li, Weihua, Lee, Philip W., Tang, Yun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2016
Gaiak:
Chemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062199/
https://ncbi.nlm.nih.gov/pubmed/30090371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00294j
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