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In silico prediction of hERG potassium channel blockage by chemical category approaches
The human ether-a-go-go related gene (hERG) plays an important role in cardiac action potential. It encodes an ion channel protein named Kv11.1, which is related to long QT syndrome and may cause avoidable sudden cardiac death. Therefore, it is important to assess the hERG channel blockage of lead c...
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| Publicado no: | Toxicol Res (Camb) |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6062199/ https://ncbi.nlm.nih.gov/pubmed/30090371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00294j |
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