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Astemizole Derivatives as Fluorescent Probes for hERG Potassium Channel Imaging

[Image: see text] The detection and imaging of hERG potassium channels in living cells can provide useful information for hERG-correlation studies. Herein, three small-molecule fluorescent probes, based on the potent hERG channel inhibitor astemizole, for the imaging of hERG channels in hERG-transfe...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Wang, Beilei, Liu, Zhenzhen, Ma, Zhao, Li, Minyong, Du, Lupei
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789673/
https://ncbi.nlm.nih.gov/pubmed/26985309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00360
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