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Astemizole-based turn-on fluorescent probes for imaging hERG potassium channel
Based on the scaffold of astemizole, three novel turn-on fluorescent probes (N1–N3) for human ether-a-go-go-related gene (hERG) potassium channel were developed herein. These probes have reasonable fluorescence properties, acceptable cell toxicity, and potent inhibitory activity, all of which contri...
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| Veröffentlicht in: | Medchemcomm |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482408/ https://ncbi.nlm.nih.gov/pubmed/31057730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00562a |
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