Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL)

The QT interval is an important diagnostic feature on surface electrocardiograms because it reflects the duration of the ventricular action potential. A previous genome-wide association study has reported a significant linkage between a single-nucleotide polymorphism ∼11.7 kb downstream of the gene...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Roder, Karim, Kabakov, Anatoli, Moshal, Karni S., Murphy, Kevin R., Xie, An, Dudley, Samuel, Turan, Nilüfer N., Lu, Yichun, MacRae, Calum A., Koren, Gideon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Protein Synthesis and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322893/
https://ncbi.nlm.nih.gov/pubmed/30401747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003852
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