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Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates
Charge variants are important attributes of monoclonal antibodies, including antibody-drug conjugates (ADCs), because charge variants can potentially influence the stability and biological activity of these molecules. Ion exchange chromatography (IEX) is widely used for charge variants analysis of m...
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| Publicado en: | MAbs |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748606/ https://ncbi.nlm.nih.gov/pubmed/31238787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1628589 |
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