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Impact of linker-drug on ion exchange chromatography separation of antibody-drug conjugates
Charge variants are important attributes of monoclonal antibodies, including antibody-drug conjugates (ADCs), because charge variants can potentially influence the stability and biological activity of these molecules. Ion exchange chromatography (IEX) is widely used for charge variants analysis of m...
Guardat en:
| Publicat a: | MAbs |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748606/ https://ncbi.nlm.nih.gov/pubmed/31238787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1628589 |
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