High-Throughput Multi-attribute Analysis of Antibody-Drug Conjugates Enabled by Trapped Ion Mobility Spectrometry and Top-Down Mass Spectrometry

Antibody-drug conjugates (ADCs) are one of the fastest growing classes of anticancer therapies. Combining the high targeting specificity of monoclonal antibodies (mAbs) with cytotoxic small molecule drugs, ADCs are complex molecular entities that are intrinsically heterogeneous. Primary sequence var...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Anal Chem
Asıl Yazarlar: Larson, Eli J., Roberts, David S., Melby, Jake A., Buck, Kevin M., Zhu, Yanlong, Zhou, Shiyue, Han, Linjie, Zhang, Qunying, Ge, Ying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319120/
https://ncbi.nlm.nih.gov/pubmed/34258999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.1c00150
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller