Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes an extensively glycosylated surface spike (S) protein to mediate host cell entry and the S protein glycosylation is strongly implicated in altering viral binding/function and infectivity. However, the structures and relative abund...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:bioRxiv
Huvudupphovsmän: Roberts, David S., Mann, Morgan W., Melby, Jake A., Larson, Eli J., Zhu, Yanlong, Brasier, Allan R., Jin, Song, Ge, Ying
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941619/
https://ncbi.nlm.nih.gov/pubmed/33688648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.28.433291
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk