Analysis of Cardiac Troponin Proteoforms by Top-Down Mass Spectrometry

The cardiac troponin complex, composed of three regulatory proteins (cTnI, cTnT, TnC), functions as the critical regulator of cardiac muscle contraction and relaxation. Myofilament protein-protein interactions are regulated by post-translational modifications (PTMs) to the protein constituents of th...

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Bibliographic Details
Published in:Methods Enzymol
Main Authors: Tiambeng, Timothy N., Tucholski, Trisha, Wu, Zhijie, Zhu, Yanlong, Mitchell, Stanford D., Roberts, David S., Jin, Yutong, Ge, Ying
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557121/
https://ncbi.nlm.nih.gov/pubmed/31606082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.07.029
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