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Bridged Hybrid Monolithic Column Coupled to High-Resolution Mass Spectrometry for Top-down Proteomics

Top-down mass spectrometry (MS)-based proteomics has become a powerful tool for comprehensive characterization of intact proteins. However, due to the high complexity of the proteome, highly effective separation of intact proteins from complex mixtures prior to MS analysis remains challenging. Monol...

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Dades bibliogràfiques
Publicat a:Anal Chem
Autors principals: Liang, Yu, Jin, Yutong, Wu, Zhijie, Tucholski, Trisha, Brown, Kyle A., Zhang, Lihua, Zhang, Yukui, Ge, Ying
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491350/
https://ncbi.nlm.nih.gov/pubmed/30668094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b05817
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