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Comprehensive Characterization of Swine Cardiac Troponin T Proteoforms by Top-down Mass Spectrometry

Cardiac Troponin T (cTnT) regulates the Ca(2+)-mediated interaction between myosin thick filaments and actin thin filaments during cardiac contraction and relaxation. cTnT is released into the blood following injury and increased serum levels of the protein is used clinically as a biomarker for myoc...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Lin, Ziqing, Guo, Fang, Gregorich, Zachery R., Sun, Ruixiang, Zhang, Han, Hu, Yang, Shanmuganayagam, Dhanansayan, Ge, Ying
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109964/
https://ncbi.nlm.nih.gov/pubmed/29633223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1925-y
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