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Comprehensive Characterization of AMP-activated Protein Kinase Catalytic Domain by Top-down Mass Spectrometry

AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that is essential in regulating energy metabolism in all eukaryotic cells. It is a heterotrimeric protein complex composed of a catalytic subunit (α) and two regulatory subunits (β and γ. C-terminal truncation of AMPKα at resid...

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Bibliographic Details
Published in:J Am Soc Mass Spectrom
Main Authors: Yu, Deyang, Peng, Ying, Ayaz-Guner, Serife, Gregorich, Zachery R., Ge, Ying
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840101/
https://ncbi.nlm.nih.gov/pubmed/26489410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1286-8
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