Top-down Proteomics in Health and Disease: Challenges and Opportunities

Por Gregorich, Zachery R., Ge, Ying
Publicado em 2014

High Throughput Screening of Disulfide-Containing Proteins in a Complex Mixture

Por Zhao, Dong S., Gregorich, Zachery R., Ge, Ying
Publicado em 2013

Proteomics in Heart Failure: Top-down or Bottom-up?

Por Gregorich, Zachery R., Chang, Ying-Hua, Ge, Ying
Publicado em 2014

Top-down Proteomics: Technology Advancements and Applications to Heart Diseases

Por Cai, Wenxuan, Tucholski, Trisha M., Gregorich, Zachery R., Ge, Ying
Publicado no Expert Rev Proteomics (2016)

Comprehensive Characterization of AMP-activated Protein Kinase Catalytic Domain by Top-down Mass Spectrometry

Por Yu, Deyang, Peng, Ying, Ayaz-Guner, Serife, Gregorich, Zachery R., Ge, Ying
Publicado no J Am Soc Mass Spectrom (2016)

Three Dimensional Liquid Chromatography Coupling IEC/HIC/RPC for Effective Protein Separation in Top-Down Proteomics

Por Valeja, Santosh G., Xiu, Lichen, Gregorich, Zachery R., Guner, Huseyin, Jin, Song, Ge, Ying
Publicado no Anal Chem (2015)

MASH Suite: A User-Friendly and Versatile Software Interface for High-Resolution Mass Spectrometry Data Interpretation and Visualization

Por Guner, Huseyin, Close, Patrick L., Cai, Wenxuan, Zhang, Han, Peng, Ying, Gregorich, Zachery R., Ge, Ying
Publicado em 2014

Distinct Sequences and Post-translational Modifications in Cardiac Atrial and Ventricular Myosin Light Chains Revealed by Top-down Mass Spectrometry

Por Gregorich, Zachery R., Cai, Wenxuan, Lin, Ziqing, Chen, Albert J., Peng, Ying, Kohmoto, Takushi, Ge, Ying
Publicado no J Mol Cell Cardiol (2017)

What Is the Impact of Phosphorylation on the Mass Spectrometry Quantification of Intact Phosphoproteins?

Por Wu, Zhijie, Tiambeng, Timothy N., Cai, Wenxuan, Chen, Bifan, Lin, Ziqing, Gregorich, Zachery R., Ge, Ying
Publicado no Anal Chem (2018)

Specific Enrichment of Phosphoproteins Using Functionalized Multivalent Nanoparticles

Por Hwang, Leekyoung, Ayaz-Guner, Serife, Gregorich, Zachery R., Cai, Wenxuan, Valeja, Santosh G., Jin, Song, Ge, Ying
Publicado no J Am Chem Soc (2015)

Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction

Por Yang, Libang, Gregorich, Zachery R., Cai, Wenxuan, Zhang, Patrick, Young, Bernice, Gu, Yiwen, Zhang, Jianyi, Ge, Ying
Publicado no J Proteome Res (2017)

Comprehensive Characterization of Swine Cardiac Troponin T Proteoforms by Top-down Mass Spectrometry

Por Lin, Ziqing, Guo, Fang, Gregorich, Zachery R., Sun, Ruixiang, Zhang, Han, Hu, Yang, Shanmuganayagam, Dhanansayan, Ge, Ying
Publicado no J Am Soc Mass Spectrom (2018)

A New Mass Spectrometry-compatible Degradable Surfactant for Tissue Proteomics

Por Chang, Ying-Hua, Gregorich, Zachery R., Chen, Albert J., Hwang, Leekyoung, Guner, Huseyin, Yu, Deyang, Zhang, Jianyi, Ge, Ying
Publicado no J Proteome Res (2015)

Top-Down Proteomics Reveals Myofilament Proteoform Heterogeneity among Various Rat Skeletal Muscle Tissues

Por Melby, Jake A., Jin, Yutong, Lin, Ziqing, Tucholski, Trisha, Wu, Zhijie, Gregorich, Zachery R., Diffee, Gary M., Ge, Ying
Publicado no J Proteome Res (2019)

Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium

Por Gregorich, Zachery R., Patel, Jitandrakumar R., Cai, Wenxuan, Lin, Ziqing, Heurer, Rachel, Fitzsimons, Daniel P., Moss, Richard L., Ge, Ying
Publicado no J Gen Physiol (2019)

MASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics

Por Cai, Wenxuan, Guner, Huseyin, Gregorich, Zachery R., Chen, Albert J., Ayaz-Guner, Serife, Peng, Ying, Valeja, Santosh G., Liu, Xiaowen, Ge, Ying
Publicado no Mol Cell Proteomics (2016)

Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry

Por Gregorich, Zachery R., Peng, Ying, Lane, Nicole M., Wolff, Jeremy J., Wang, Sijian, Guo, Wei, Guner, Huseyin, Doop, Justin, Hacker, Timothy A., Ge, Ying
Publicado no J Mol Cell Cardiol (2015)

Temperature-sensitive Sarcomeric Protein Post-translational Modifications Revealed by Top-down Proteomics

Por Cai, Wenxuan, Hite, Zachary L., Lyu, Beini, Wu, Zhijie, Lin, Ziqing, Gregorich, Zachery R., Messer, Andrew E., McIlwain, Sean, Marston, Steve B., Kohmoto, Takushi, Ge, Ying
Publicado no J Mol Cell Cardiol (2018)

Top-down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light Chain Phosphorylation that Contributes to Sarcopenic Muscle Dysfunction

Por Gregorich, Zachery R., Peng, Ying, Cai, Wenxuan, Jin, Yutong, Wei, Liming, Chen, Albert J., McKiernan, Susan H., Aiken, Judd M., Moss, Richard L., Diffee, Gary M., Ge, Ying
Publicado no J Proteome Res (2016)

Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics

Por Wei, Liming, Gregorich, Zachery R., Lin, Ziqing, Cai, Wenxuan, Jin, Yutong, McKiernan, Susan H., McIlwain, Sean, Aiken, Judd M., Moss, Richard L., Diffee, Gary M., Ge, Ying
Publicado no Mol Cell Proteomics (2018)