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Three Dimensional Liquid Chromatography Coupling IEC/HIC/RPC for Effective Protein Separation in Top-Down Proteomics
To address the complexity of proteome in mass spectrometry (MS)-based top-down proteomics, multi-dimensional liquid chromatography (MDLC) strategies that can effectively separate proteins with high resolution and automation are highly desirable. Although various MDLC methods that can effectively sep...
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Publicado no: | Anal Chem |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575680/ https://ncbi.nlm.nih.gov/pubmed/25867201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b00657 |
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