Comprehensive assessment of chamber-specific and transmural heterogeneity in myofilament protein phosphorylation by top-down mass spectrometry

The heart is characterized by a remarkable degree of heterogeneity, the basis of which is a subject of active investigation. Myofilament protein post-translational modifications (PTMs) represent a critical mechanism regulating cardiac contractility, and emerging evidence shows that pathological card...

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Publicat a:J Mol Cell Cardiol
Autors principals: Gregorich, Zachery R., Peng, Ying, Lane, Nicole M., Wolff, Jeremy J., Wang, Sijian, Guo, Wei, Guner, Huseyin, Doop, Justin, Hacker, Timothy A., Ge, Ying
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637236/
https://ncbi.nlm.nih.gov/pubmed/26268593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.08.007
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