Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

Heart failure (HF) is a leading cause of morbidity and mortality worldwide and is most often precipitated by myocardial infarction. However, the molecular changes driving cardiac dysfunction immediately after myocardial infarction remain poorly understood. Myofilament proteins, responsible for cardi...

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Autori principali: Peng, Ying, Gregorich, Zachery R., Valeja, Santosh G., Zhang, Han, Cai, Wenxuan, Chen, Yi-Chen, Guner, Huseyin, Chen, Albert J., Schwahn, Denise J., Hacker, Timothy A., Liu, Xiaowen, Ge, Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189000/
https://ncbi.nlm.nih.gov/pubmed/24969035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.040675
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