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Comprehensive Characterization of Recombinant Catalytic Subunit of cAMP-Dependent Protein Kinase by Top-Down Mass Spectrometry

Reversible phosphorylation plays critical roles in cell growth, division, and signal transduction. Kinases which catalyze the transfer of γ-phosphate groups of nucleotide triphosphates to their substrates are central to the regulation of protein phosphorylation and are therefore important therapeuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Mass Spectrom
Hauptverfasser: Wu, Zhijie, Jin, Yutong, Chen, Bifan, Gugger, Morgan K., Wilkinson-Johnson, Chance L., Tiambeng, Timothy N., Jin, Song, Ge, Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922056/
https://ncbi.nlm.nih.gov/pubmed/31792770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-019-02341-0
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