Single-molecule correlated chemical probing reveals large-scale structural communication in the ribosome and the mechanism of the antibiotic spectinomycin in living cells

The ribosome moves between distinct structural states and is organized into multiple functional domains. Here, we examined hundreds of occurrences of pairwise through-space communication between nucleotides in the ribosome small subunit RNA using RNA interaction groups analyzed by mutational profili...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Sengupta, Arnab, Rice, Greggory M., Weeks, Kevin M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748448/
https://ncbi.nlm.nih.gov/pubmed/31487286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000393
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