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SHAPE probing reveals human ribosomal RNAs are largely unfolded in solution
Chemical probing experiments, coupled with empirically-determined free energy change relationships, can enable accurate modeling of the secondary structures of diverse and complex RNAs. A current frontier lies in modeling large and structurally heterogeneous transcripts, including complex eukaryotic...
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| Publicado en: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687064/ https://ncbi.nlm.nih.gov/pubmed/31305988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00076 |
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