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Guidelines for SHAPE reagent choice and detection strategy for RNA structure probing studies
Chemical probing is an important tool for characterizing the complex folded structures of RNA molecules, many of which play key cellular roles. Electrophilic SHAPE reagents create adducts at the 2'-hydroxyl position on the RNA backbone of flexible ribonucleotides with relatively little dependen...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712974/ https://ncbi.nlm.nih.gov/pubmed/31117385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01218 |
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