Pervasive regulatory functions of mRNA structure revealed by high-resolution SHAPE probing

Messenger RNAs (mRNAs) can fold into complex structures that regulate gene expression. Resolving such structures de novo has remained challenging and has limited understanding of the prevalence and functions of mRNA structure. We use SHAPE-MaP experiments in living E. coli cells to derive quantitati...

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Publicat a:Cell
Autors principals: Mustoe, Anthony M., Busan, Steven, Rice, Greggory M., Hajdin, Christine E., Peterson, Brant K., Ruda, Vera, Kubica, Neil, Nutiu, Razvan, Baryza, Jeremy L., Weeks, Kevin M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866243/
https://ncbi.nlm.nih.gov/pubmed/29551268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.034
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