Pervasive regulatory functions of mRNA structure revealed by high-resolution SHAPE probing

Messenger RNAs (mRNAs) can fold into complex structures that regulate gene expression. Resolving such structures de novo has remained challenging and has limited understanding of the prevalence and functions of mRNA structure. We use SHAPE-MaP experiments in living E. coli cells to derive quantitati...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Mustoe, Anthony M., Busan, Steven, Rice, Greggory M., Hajdin, Christine E., Peterson, Brant K., Ruda, Vera, Kubica, Neil, Nutiu, Razvan, Baryza, Jeremy L., Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866243/
https://ncbi.nlm.nih.gov/pubmed/29551268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.034
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