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RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

Many biological processes are RNA-mediated, but higher-order structures for most RNAs are unknown, making it difficult to understand how RNA structure governs function. Here we describe SHAPE mutational profiling (SHAPE-MaP) that makes possible de novo and large-scale identification of RNA functiona...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Siegfried, Nathan A., Busan, Steven, Rice, Greggory M., Nelson, Julie A.E., Weeks, Kevin M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259394/
https://ncbi.nlm.nih.gov/pubmed/25028896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3029
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