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RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
Many biological processes are RNA-mediated, but higher-order structures for most RNAs are unknown, making it difficult to understand how RNA structure governs function. Here we describe SHAPE mutational profiling (SHAPE-MaP) that makes possible de novo and large-scale identification of RNA functiona...
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Publicado no: | Nat Methods |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259394/ https://ncbi.nlm.nih.gov/pubmed/25028896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3029 |
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