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In-cell RNA structure probing with SHAPE-MaP

RNAs play key roles in many cellular processes. The underlying structure of RNA is an important determinant for how transcripts function, are processed, and interact with RNA-binding proteins and ligands. RNA structure analysis by selective 2’-hydroxyl acylation analyzed by primer extension (SHAPE)...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Smola, Matthew J., Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402486/
https://ncbi.nlm.nih.gov/pubmed/29725122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2018.010
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