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Fingerprinting Non-Canonical and Tertiary RNA Structures by Differential SHAPE Reactivity

Many RNA structures are comprised of simple secondary structure elements linked by a few, critical, tertiary interactions. SHAPE chemistry has made interrogation of RNA dynamics at single-nucleotide resolution straightforward. However, de novo identification of nucleotides involved in tertiary inter...

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Detalhes bibliográficos
Main Authors: Steen, Kady-Ann, Rice, Greggory M., Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425954/
https://ncbi.nlm.nih.gov/pubmed/22852530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja304027m
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