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RNA tertiary structure analysis by 2'-hydroxyl molecular interference

We introduce a melded chemical and computational approach for probing and modeling higher-order intramolecular tertiary interactions in RNA. 2'-Hydroxyl molecular interference (HMX) identifies nucleotides in highly packed regions of an RNA by exploiting the ability of bulky adducts at the 2...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Homan, Philip J., Tandon, Arpit, Rice, Greggory M., Ding, Feng, Dokholyan, Nikolay V., Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903172/
https://ncbi.nlm.nih.gov/pubmed/25341083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501218g
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