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Native-like RNA tertiary structures using a sequence-encoded cleavage agent and refinement by discrete molecular dynamics

The difficulty of analyzing higher order RNA structure, especially for folding intermediates and for RNAs whose functions require domains that are conformationally flexible, emphasizes the need for new approaches for modeling RNA tertiary structure accurately. Here, we report a concise approach that...

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Hlavní autoři: Gherghe, Costin M., Leonard, Christopher W., Ding, Feng, Dokholyan, Nikolay V., Weeks, Kevin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664099/
https://ncbi.nlm.nih.gov/pubmed/19193004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805460e
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