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Three-Dimensional RNA Structure Refinement by Hydroxyl Radical Probing

Molecular modeling guided by experimentally-derived structural information is an attractive approach for three-dimensional structure determination of complex RNAs that are not amenable to study by high-resolution methods. Hydroxyl radical probing (HRP), performed routinely in many laboratories, prov...

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Detalles Bibliográficos
Main Authors: Ding, Feng, Lavender, Christopher A., Weeks, Kevin M., Dokholyan, Nikolay V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422565/
https://ncbi.nlm.nih.gov/pubmed/22504587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1976
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