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Structure modeling of RNA using sparse NMR constraints

RNAs fold into distinct molecular conformations that are often essential for their functions. Accurate structure modeling of complex RNA motifs, including ubiquitous non-canonical base pairs and pseudoknots, remains a challenge. Here, we present an NMR-guided all-atom discrete molecular dynamics (DM...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Williams, Benfeard, Zhao, Bo, Tandon, Arpit, Ding, Feng, Weeks, Kevin M., Zhang, Qi, Dokholyan, Nikolay V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728392/
https://ncbi.nlm.nih.gov/pubmed/29165648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1058
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