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Selective Inhibition of Initiating Ribosomes by Spectinomycin

Spectinomycin at low concentrations inhibits initiating ribosomes but not ribosomes already engaged in chain elongation. The initiating ribosomes are blocked in some step after formation of the initiation complex, probably the first translocation. Cells inhibited by spectinomycin accumulate polysome...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wallace, Brian J., Tai, Phang-Cheng, Davis, Bernard D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1974
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC388291/
https://ncbi.nlm.nih.gov/pubmed/4275941
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