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SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability
SPOP is one of the important subunits for CUL3/SPOP/RBX1 complex tightly connected with tumorigenesis. However, its exact roles in different cancers remain debatable. Here, we identify CYCLIN E1, as a novel substrate for SPOP. SPOP directly interacts with CYCLIN E1 and specific regulates its stabili...
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| 發表在: | Cell Death Differ |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748103/ https://ncbi.nlm.nih.gov/pubmed/30237511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0198-0 |
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