SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing

Trimethylation of histone H3K36 is a chromatin mark associated with active gene expression, which has been implicated in coupling transcription with mRNA splicing and DNA damage response. SETD2 is a major H3K36 trimethyltransferase, which has been implicated as a tumor suppressor in mammals. Here, w...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Zhu, Kun, Lei, Pin-Ji, Ju, Lin-Gao, Wang, Xiang, Huang, Kai, Yang, Bo, Shao, Changwei, Zhu, Yuan, Wei, Gang, Fu, Xiang-Dong, Li, Lianyun, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224501/
https://ncbi.nlm.nih.gov/pubmed/27614073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw814
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