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Regulation of SETD2 stability is important for the fidelity of H3K36me3 deposition

BACKGROUND: The histone H3K36me3 mark regulates transcription elongation, pre-mRNA splicing, DNA methylation, and DNA damage repair. However, knowledge of the regulation of the enzyme SETD2, which deposits this functionally important mark, is very limited. RESULTS: Here, we show that the poorly char...

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Bibliografische gegevens
Gepubliceerd in:Epigenetics Chromatin
Hoofdauteurs: Bhattacharya, Saikat, Workman, Jerry L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542105/
https://ncbi.nlm.nih.gov/pubmed/33023640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00362-8
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