Identification of SPOP related metabolic pathways in prostate cancer

Speckle-type POZ protein (SPOP), as a cullin-based E3 ubiquitin ligase, has been identified as one of the most frequently mutated genes in prostate cancer (PCa). However, whether SPOP mutations contribute to metabolic reprogramming in PCa remains unknown. Here, integrated studies of transcriptomics...

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Publicat a:Oncotarget
Autors principals: Yan, Min, Qi, Huan, Li, Jia, Ye, Guozhu, Shao, Yaping, Li, Tongming, Liu, Jing, Piao, Hai-Long, Xu, Guowang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732708/
https://ncbi.nlm.nih.gov/pubmed/29262542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21460
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