Identification of SPOP related metabolic pathways in prostate cancer

Speckle-type POZ protein (SPOP), as a cullin-based E3 ubiquitin ligase, has been identified as one of the most frequently mutated genes in prostate cancer (PCa). However, whether SPOP mutations contribute to metabolic reprogramming in PCa remains unknown. Here, integrated studies of transcriptomics...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Yan, Min, Qi, Huan, Li, Jia, Ye, Guozhu, Shao, Yaping, Li, Tongming, Liu, Jing, Piao, Hai-Long, Xu, Guowang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732708/
https://ncbi.nlm.nih.gov/pubmed/29262542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21460
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