Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila

Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O’nyong nyong (ONNV) viruses. To determine its role in pathogenesis, we generated mice with mutant Mxra8 alleles: an 8-nucleotide deletion that produces a truncated,...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Zhang, Rong, Earnest, James T., Kim, Arthur S., Winkler, Emma S., Desai, Pritesh, Adams, Lucas J., Hu, Gaowei, Bullock, Christopher, Gold, Beth, Cherry, Sara, Diamond, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745702/
https://ncbi.nlm.nih.gov/pubmed/31484075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.105
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