Mxra8 is a receptor for multiple arthritogenic alphaviruses

Arthritogenic alphaviruses comprise a group of enveloped RNA viruses that are transmitted to humans by mosquitoes and cause debilitating acute and chronic musculoskeletal disease(1). The host factors required for alphavirus entry remain poorly characterized(2). Using a genome-wide CRISPR/Cas9-based...

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Publicado no:Nature
Main Authors: Zhang, Rong, Kim, Arthur S., Fox, Julie M., Nair, Sharmila, Basore, Katherine, Klimstra, William B., Rimkunas, Rebecca, Fong, Rachel H., Lin, Hueylie, Poddar, Subhajit, Crowe, James E., Doranz, Benjamin J., Fremont, Daved H., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970976/
https://ncbi.nlm.nih.gov/pubmed/29769725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0121-3
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