Mxra8 is a receptor for multiple arthritogenic alphaviruses

Arthritogenic alphaviruses comprise a group of enveloped RNA viruses that are transmitted to humans by mosquitoes and cause debilitating acute and chronic musculoskeletal disease(1). The host factors required for alphavirus entry remain poorly characterized(2). Using a genome-wide CRISPR/Cas9-based...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Zhang, Rong, Kim, Arthur S., Fox, Julie M., Nair, Sharmila, Basore, Katherine, Klimstra, William B., Rimkunas, Rebecca, Fong, Rachel H., Lin, Hueylie, Poddar, Subhajit, Crowe, James E., Doranz, Benjamin J., Fremont, Daved H., Diamond, Michael S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970976/
https://ncbi.nlm.nih.gov/pubmed/29769725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0121-3
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